Gut microbiota and pediatric obesity/non-alcoholic fatty liver disease

Dec 5, 2018Journal of the Formosan Medical Association = Taiwan yi zhi

Gut bacteria linked to childhood obesity and fatty liver disease

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Abstract

Dysbiosis in gut microbiota is associated with pediatric diseases, including obesity and non-alcoholic fatty liver disease (NAFLD).

  • The gut microbiome plays a significant role in the development and regulation of the immune system.
  • Factors such as gestational age, delivery method, feeding sources, and antibiotic use can influence gut microbial diversity in neonates.
  • Disturbances in gut microbiota, referred to as dysbiosis, have been linked to various pediatric conditions.
  • Currently, no specific microbial species have been definitively identified as key contributors to pediatric obesity or NAFLD.
  • Probiotics may offer potential benefits for conditions related to gut microbiota in children, but clinical applications remain limited.

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