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Abstract
Nonalcoholic fatty liver disease (NAFLD) is one of the most common types of liver diseases worldwide, with increasing incidence.
- NAFLD occurs when excess energy cannot be effectively stored in adipose tissue.
- The gut-liver axis, connected via the portal vein, plays a significant role in NAFLD.
- Dysbiosis, or imbalance, of the gut microbiome is associated with NAFLD pathophysiology.
- Therapeutic strategies to manipulate gut microbiota include probiotics, prebiotics, synbiotics, and antibiotics.
- Numerous initial reports suggest potential effectiveness of these novel therapies in managing NAFLD.
- Ongoing clinical trials are exploring these approaches for the prevention and management of NAFLD.
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