How Imbalance in Gut Bacteria Is Linked to Fatty Liver Disease and the Potential Role of Probiotics

Gut microbiota dysbiosis significantly contributes to the pathogenesis and severity of nonalcoholic fatty liver disease (NAFLD).

• The role of gut microbiota in NAFLD is complex and not fully understood.
• Chemotherapeutic treatments for NAFLD face scrutiny due to potential health side effects.
• Key mechanisms of gut dysbiosis are linked to the progression of NAFLD and liver cirrhosis.
• Probiotics have shown promising effects in alleviating gut microbiota dysbiosis.
• Microbiota-targeted interventions could regulate metabolic pathways to inhibit NAFLD progression.
• Current human studies on probiotics and NAFLD are very limited, indicating a need for further research.

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