Frontiers in psychiatry

How gut bacteria influence the antidepressant effects of natural polysaccharides targeting multiple systems

Updated

Abstract

Natural polysaccharides may improve depression symptoms through modulation of gut microbiota.

  • Depression presents with emotional, physiological, and behavioral symptoms.
  • Natural polysaccharides are noted for their low toxicity.
  • Preclinical evidence suggests potential antidepressant effects of natural polysaccharides.
  • Modulation of gut microbiota may be involved in the antidepressant mechanisms.
  • The review explores connections between gut microbiota and brain function.

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Full Text

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Funding

Competing interests

The author(s) declared that this work was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The reviewer SL declared a shared affiliation with author CB to the handling editor at the time of review.
PubMed

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