The interplay between heart failure and chronic kidney disease

Apr 22, 2025Diabetes, obesity & metabolism

How heart failure and chronic kidney disease affect each other

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Abstract

Approximately 50% of all individuals with (HF) also have (CKD).

  • CKD and HF often coexist and can worsen each other, creating a cycle of declining health.
  • Common risk factors for both conditions include age, diabetes, high blood pressure, obesity, and smoking.
  • Having both CKD and HF significantly increases the risk of hospitalization and mortality compared to having either condition alone.
  • Understanding the systemic nature of these diseases can enhance treatment effectiveness for patients with both conditions.
  • Certain medications, such as renin-angiotensin system inhibitors and sodium-glucose cotransporter 2 inhibitors, play important roles in managing CKD and HF.

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Key numbers

9.1%
Prevalence
Global prevalence of in 2017.
64 million
Prevalence
Number of people affected by worldwide.
50%
in Patients
Proportion of patients who also have .

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