Nature cardiovascular research

Genetic Links Between Blood Clots and Long COVID in People of European Descent

Updated

Abstract

Essence

Human genetic analyses suggest thromboembolism may contribute to long COVID in people of European ancestry.

Evidence

This host-genetics analysis in the Long COVID Host Genetics Initiative found genetically predicted venous thromboembolism risk was associated with 1.21-fold higher odds of long COVID and pointed to PAR-1 in downstream analyses.

Caveat

The evidence is genetic association in European-ancestry datasets rather than direct mechanistic or interventional proof, so generalizability and causality remain limited.

Simplified

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Funding

Competing interests

8 of 22
authors report competing interests
14 report none
PubMed

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