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Inflammatory aspects of Alzheimer’s disease
Inflammation in Alzheimer's Disease
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Abstract
Alzheimer's disease (AD) is the most common chronic neurodegenerative disorder, characterized by cognitive decline and memory loss.
- Neurodegeneration is the primary pathological feature of Alzheimer's disease.
- Microglia, the brain's resident immune cells, play a crucial role in neuroinflammation associated with AD.
- Astrocytes are also significant contributors to the neuroinflammatory process in AD.
- Interactions between microglia and astrocytes are linked to the disease's core pathologies, including amyloid beta deposition and tau tangle formation.
- Different forms of regulated cell death in AD may influence the chronic neuroinflammatory environment.
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