Using intravenous ketamine for patients in a suicidal crisis: when and how they are referred

Intravenous (IV) ketamine may rapidly reduce suicidal ideation and psychological distress within hours.

• IV ketamine is a therapeutic option specifically for treatment-resistant depression and acute suicidal crisis.
• Its effects are distinct from conventional antidepressants, which typically take longer to act.
• Hospital-based care is necessary for its administration, involving medical monitoring and psychiatric assessment.
• The article outlines indications and referral criteria for primary care physicians regarding IV ketamine use.

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