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Effects of inulin on intestinal flora and metabolism-related indicators in obese polycystic ovary syndrome patients
Inulin’s effects on gut bacteria and metabolism in obese women with polycystic ovary syndrome
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Abstract
After 3 months of treatment, dietary improved sex hormone disorders and reduced BMI and WHR levels in obese women with .
- Dietary inulin reduced plasma levels of inflammatory markers TNF-α, IL-1β, IL-6, and MCP-1.
- Inulin treatment increased the abundance of beneficial gut bacteria such as Actinobacteria, Fusobacteria, and Bifidobacterium.
- The ratio of Firmicutes to Bacteroidetes (F/B) decreased following inulin intervention.
- A strong correlation was observed among plasma inflammatory factors, sex steroid hormones, and the intestinal flora in patients.
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Key numbers
0.046
Decrease in BMI
Statistical significance of BMI reduction after intervention.
Significant increase
Increased Actinobacteria abundance
Change in gut microbiota composition after treatment.
Significant decrease
Decrease in inflammatory markers
Reduction in plasma inflammatory markers after treatment.