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Abstract
Anesthetic doses of ketamine are associated with deficits in mitochondrial viability and function.
- Mitochondrial dysfunction may play a role in the development of depressive disorders.
- Antidepressant doses of ketamine and esketamine have shown rapid effects in treating challenging depressive disorders.
- The literature synthesis focuses on comparing the effects of ketamine and esketamine on mitochondrial function in living organisms versus laboratory settings.
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