American journal of physiology. Renal physiology

New Insights into How the Kidney’s Internal Clock Works

Updated

Abstract

Circadian rhythms regulate kidney function, influencing homeostasis and metabolic waste excretion.

  • The kidney's role in maintaining water and electrolyte balance is influenced by circadian rhythms.
  • Blood pressure regulation in the kidney also displays a pattern linked to the time of day.
  • Disrupted circadian rhythms may negatively impact kidney health.
  • Understanding molecular mechanisms of circadian regulation in the kidney has advanced significantly in the past decade.
  • Future research should consider the time of day as a critical variable in kidney studies.

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