Life’s Essential 8 and the risk of cardiovascular disease death and all-cause mortality in Finnish men

A total LE8 score among participants ranged from 185 to 750.

• Higher LE8 scores are associated with a lower risk of dying from cardiovascular disease (CVD) and all-cause mortality.
• Every 50-unit increase in LE8 score is linked to a 17% lower risk of CVD deaths and a 14% lower risk of all-cause deaths.
• Men in the top quartile of LE8 scores have a 60% lower risk of CVD mortality compared to those in the bottom quartile.
• The study involved 1662 men aged 42-60 years without pre-existing cardiovascular disease at baseline.
• The median follow-up period for the participants was 30 years.

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