Effects of liposomal bupivacaine in preoperative fascia iliac block on postoperative pain and delirium in elderly patients undergoing hip fracture surgery: a study protocol for a randomised, parallel controlled prospective clinical study

Jan 6, 2024BMJ open

Liposomal bupivacaine in pre-surgery nerve block and its effects on pain and delirium after hip fracture surgery in older patients

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Abstract

The occurrence of (POD) will be evaluated in a randomized clinical study involving liposomal bupivacaine and ropivacaine for hip fracture surgery.

  • Postoperative delirium is the most common acute mental state change after hip fractures in older adults.
  • Postoperative pain is identified as a Grade A risk factor for the development of POD.
  • The may effectively reduce the incidence of POD in patients undergoing hip fracture surgery.
  • Liposomal bupivacaine has a long half-life and may decrease opioid consumption, potentially improving patient recovery.
  • The study aims to clarify whether regional nerve block analgesia can reduce POD occurrences in elderly patients.

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