Journal of endocrinological investigation

Effectiveness and safety of liraglutide, semaglutide, and tirzepatide for treating overweight and obesity

Updated

Abstract

The introduction of a 7.2 mg maintenance dose of semaglutide is under evaluation for its efficacy and safety in managing obesity.

  • Comparative evidence is needed for long-term pharmacotherapy to address the global rise in overweight and obesity.
  • The study focuses on glucagon-like peptide-1 (GLP-1) receptor agonists, including liraglutide, semaglutide, and tirzepatide.
  • The incremental value of semaglutide at the 7.2 mg dose is a key point of assessment.
  • Efficacy and safety outcomes of these treatments are being evaluated in the context of obesity management.

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