The body’s internal clock and how timing affects drug responses

Recent advances in understanding the molecular control of circadian rhythms may lead to new therapeutic drug targets.

• The molecular clock in mammals plays a critical role in regulating circadian rhythms.
• Targeting components of the molecular clock could enhance the development of novel therapeutics.
• Circadian rhythms may influence the effectiveness and safety of existing drugs.
• Improved knowledge of these mechanisms is associated with the potential for more efficacious drug utilization.

Simplified