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The efficacy and safety of MDMA-assisted psychotherapy for treatment of posttraumatic stress disorder: A systematic review and meta-analysis from randomized controlled trials
MDMA-assisted psychotherapy for posttraumatic stress disorder: effectiveness and safety based on controlled trials
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Abstract
Seven randomized controlled trials indicate that MDMA-assisted psychotherapy significantly reduces PTSD symptoms compared to placebo or active controls.
- MDMA-assisted psychotherapy is associated with a reduction in PTSD symptoms as measured by the Clinician-Administered PTSD Scale.
- Adverse events linked to MDMA include muscle tightness, nausea, and decreased appetite.
- While MDMA-assisted psychotherapy may improve PTSD symptoms, concerns related to side effects and potential for abuse limit its clinical use.
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