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Abstract
The global prevalence of aging and age-related diseases is rising due to increased life expectancy and a growing aging population.
- Multiple strategies may slow aging and extend lifespan, including metabolic modulation, targeting inflammation, and senotherapy.
- Preclinical models have shown promise for interventions like physical exercise, calorie restriction, and stem cell-based therapies.
- Some anti-aging strategies have demonstrated efficacy in clinical trials.
- Key mechanisms involved in these interventions include enhancing cellular cleanup processes, removing damaged cells, and improving mitochondrial function.
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