Rejuvenation research

Melatonin shortage and its possible link to delirium: a summary of current research

Updated

Abstract

Melatonin deficiency is associated with circadian rhythm disorders in patients with delirium and cognitive impairment.

  • Delirium symptoms often overlap with those of dementia, including issues like sundowning.
  • Circadian rhythm disturbances are common in individuals experiencing delirium.
  • Melatonin plays a significant role in regulating the sleep-wake cycle in mammals.
  • Therapeutic benefits of melatonin treatment have been observed in disorders related to delirium and dementia.
  • Placebo-controlled randomized clinical trials have explored melatonin's effects in these patient populations.

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