Kidney international

New possible treatment targets for kidney disease linked to metabolic problems and diabetes

Updated

Abstract

Individuals with metabolic syndrome are at an increased risk of developing chronic kidney disease.

  • Metabolic syndrome is linked to both chronic kidney disease and the progression of existing kidney conditions.
  • There is a higher likelihood of developing diabetes among individuals with metabolic syndrome, which may lead to diabetic kidney disease.
  • Current treatments for diabetic kidney disease include several classes of medications that offer significant protection for the kidneys.
  • Despite existing treatments, diabetic kidney disease continues to persist and progress, indicating a need for new therapeutic approaches.
  • Emerging targets from preclinical models suggest potential pathways for developing novel treatments aimed at kidney protection.

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