Crosstalk between metabolism and circadian clocks

Jan 13, 2019Nature reviews. Molecular cell biology

Interaction between Body Metabolism and Internal Biological Clocks

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Abstract

The circadian clock plays a crucial role in aligning metabolic processes with daily activity patterns.

  • Circadian rhythms are regulated by a master clock in the brain that responds to light and darkness.
  • Each cell contains its own circadian oscillator that works in conjunction with the master clock to maintain rhythmicity.
  • Metabolic regulation actively influences the circadian system, signaling back to cellular clocks based on nutrient and energy levels.
  • Disruption of the connection between circadian rhythms and metabolism may contribute to various health issues.

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