We can’t show the full text here under this license.
Aging Clocks Based on Metabolic Chemicals
Updated
Abstract
Essence
NMR-based metabolomic aging clocks may make biological-age estimates more clinically interpretable by linking metabolic patterns to disease-specific distortions.
Evidence
This review and model-description paper summarizes NMR-based metabolomic clock approaches and presents a new clinically interpretable method for risk stratification and early detection of accelerated aging.
Caveat
The abstract does not report validation cohorts, sample sizes, comparative performance numbers, or clinical outcome testing for the new approach.
Simplified
Key numbers
0.92
Correlation Coefficient
for the on the test set.
17,345 individuals
Sample Size
Participants from the Estonian cohort analyzed for mortality prediction.
4068 urine samples
Sample Size
Samples collected for developing a metabolomic approach to estimate biological age.
Longevity & Aging