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Abstract
Essence
NMR-based metabolomic aging clocks may make biological-age estimates more clinically interpretable by linking metabolic patterns to disease-specific distortions.
Evidence
This review and model-description paper summarizes NMR-based metabolomic clock approaches and presents a new clinically interpretable method for risk stratification and early detection of accelerated aging.
Caveat
The abstract does not report validation cohorts, sample sizes, comparative performance numbers, or clinical outcome testing for the new approach.
Simplified