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Neuroimmunometabolism: how metabolism orchestrates immune response in healthy and diseased brain
How Metabolism Controls the Brain's Immune Response in Health and Disease
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Abstract
Neuroimmunometabolism explores how microglia adjust their metabolism to influence immune functions in the central nervous system.
- Microglia alter their metabolic pathways to modify immune responses in the brain.
- Neurons may communicate with microglia and influence their immune functions through metabolic signals.
- The metabolic environment of the brain and microglial metabolism play critical roles in neuroimmune responses in both healthy and diseased states.
- Dysregulation of metabolic substrates could impact neuroimmune responses and contribute to psychiatric disorders.
- Metabolic reprogramming of microglia is proposed as a potential strategy for managing neuroinflammation-related brain disorders.
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