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Night Shift Work and Levels of 6-Sulfatoxymelatonin and Cortisol in Men
Night shift work linked to changes in melatonin and stress hormone levels in men
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Abstract
Night shift workers had 57% lower levels of 6-sulfatoxymelatonin during daytime sleep compared to day shift workers.
- Night shift workers showed significantly lower 6-sulfatoxymelatonin levels during nighttime work and nighttime sleep on off-nights, with reductions of 62% and 40% respectively.
- Urinary cortisol levels in night shift workers were 16% higher during daytime sleep and 13% lower during nighttime sleep on off-nights compared to day shift workers.
- Morning serum cortisol levels post-work and post-sleep in night shift workers were 24% and 43% lower than those of day shift workers.
- Within-night shift workers, melatonin levels were significantly lower during daytime sleep and nighttime work compared to nighttime sleep.
- Cortisol secretion patterns in night shift workers may be altered, which could be associated with increased cancer risk.
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