OS-2 Mitogen Activated Protein Kinase Regulates the Clock-Controlled Geneccg-1inNeurospora crassa

OS-2 MAP kinase is involved in osmoadaptation in Neurospora crassa.

• Osmotic stress induced the expression of clock-controlled genes ccg-1, bli-3, and con-10 in an OS-2 dependent manner.
• Clock genes frq, wc-1, and wc-2 were not affected by osmotic stress.
• The expression of other clock-controlled genes, ccg-2 and bli-4, remained unchanged during osmotic stress.
• These findings suggest that OS-2 may regulate specific circadian-clock output genes.

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