Phytomedicine : international journal of phytotherapy and phytopharmacology

Perillaldehyde may ease Parkinson's disease through gut bacteria and a key blood chemical pathway

Gut-Brain Axis Weekly Brief ↗PubMed ↗DOI ↗

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Abstract

Perillaldehyde (PAH) has significant neuroprotective and anti-inflammatory properties in vitro.

  • Gut microbiota dysbiosis is linked to the development of Parkinson's disease (PD).
  • Therapeutic strategies targeting the gut-brain axis in PD are currently underexplored.
  • PAH is derived from the plant Perilla frutescens and may influence the mechanisms related to microbiota.
  • The effects of PAH on PD in living organisms are not yet fully understood.

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