Pharmacological management of co-morbid obstructive sleep apnoea and insomnia

Approximately 30% of clinical cohorts with obstructive sleep apnea also exhibit insomnia symptoms.

• The clinical presentation of insomnia and obstructive sleep apnea often overlaps, complicating diagnosis and treatment.
• Current management options primarily include continuous positive airway pressure therapy and cognitive behavioral therapy for insomnia.
• Emerging pharmacotherapies for insomnia may not address the underlying causes and are recommended for short-term use only.
• Lack of clinical trial data specific to the combined condition of insomnia and obstructive sleep apnea is noted as a significant gap.
• Future research should focus on the multifactorial nature of the condition and the practical barriers faced by healthcare providers and patients.

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