Post-transcriptional control of circadian rhythms

Jan 19, 2011Journal of cell science

How cells control daily body clocks after gene activation

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Abstract

Post-transcriptional regulation is crucial for robust circadian rhythms across various organisms.

  • Circadian rhythms are present in most living organisms and are generated by conserved molecular mechanisms.
  • Core circadian clocks consist of multiple regulatory feedback loops that require precise coordination.
  • Post-transcriptional regulation has been shown to significantly affect the phase and amplitude of mRNA and protein expression.
  • Current knowledge highlights the role of post-transcriptional mechanisms in the modulation of circadian gene expression in dinoflagellates, plants, fungi, and animals.
  • Understanding these regulatory processes is important for maintaining the stability of circadian rhythms.

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