Posttranscriptional mechanisms in controlling eukaryotic circadian rhythms

Mar 19, 2011FEBS letters

How RNA-level processes control daily biological clocks in complex cells

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Abstract

The circadian clock is essential for synchronizing cycles in all living organisms.

  • The circadian clock is controlled by multiple positive and negative molecular mechanisms that regulate gene expression.
  • Recent studies have identified additional regulatory components that fine-tune the circadian system at the posttranslational level.
  • Posttranscriptional regulation has been shown to control the expression of both circadian oscillator and output gene transcripts.
  • This regulation is crucial for maintaining robust circadian rhythms.
  • Advances in research have focused on the role of RNA in circadian rhythm regulation.

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