JAMA health forum

Compounded GLP-1 Receptor Agonist Use After Shortages in Two States with Likely High Demand

Updated

Abstract

A robust market for compounded glucagon-like peptide-1 receptor agonists (GLP-1 RAs) emerged due to supply-side challenges and high costs.

  • The market dynamics for GLP-1 RAs have shifted since shortages of semaglutide and tirzepatide ended.
  • High costs and limited insurance coverage may continue to influence the accessibility of GLP-1 RAs.
  • Understanding current market trends is essential for evaluating the availability of these medications.

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