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Impact of pre-existing comorbidities and multimorbidities, demography and viral variants on post-acute sequelae of COVID-19 (‘Long COVID’) in Dutch primary care: A retrospective cohort study
How health conditions, age, and COVID-19 variants relate to Long COVID in Dutch primary care
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Abstract
PASC prevalence was 5.8% among 19,638 SARS-CoV-2 PCR-positive patients.
- Chronic lung disease, cardiovascular disease, diabetes, kidney disease, and mental illness are associated with increased risk of PASC.
- The relative risk for developing PASC is highest for kidney disease (RR: 1.98) and lung disease (RR: 1.95).
- Females and individuals aged 45 and older are at a higher risk for PASC.
- Prolonged PASC is more likely in individuals aged 45-59 (adjusted odds ratio: 3.02), 60-74 (3.25), and 75+ (2.44).
- Having both mental illness and lung disease significantly increases the risk of prolonged PASC (AOR: 2.55).
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