Biochemical and biophysical research communications

Targeted gene correction of TP53 mutations to restore tumor suppression in colorectal cancer

Updated

Abstract

Colorectal cancer (CRC) has a high mortality rate associated with genetic diversity and treatment resistance.

  • TP53 mutations are significant molecular alterations linked to CRC.
  • These mutations may disrupt genomic stability.
  • TP53 is considered a key target for personalized treatment strategies.
  • The genetic heterogeneity of CRC contributes to challenges in effective treatment.

Simplified

Full Text

Full text is available at the source.

Funding

Competing interests

No competing interests reported.
PubMed

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