Factors linked to serious heart problems around the time of weight-loss surgery

Among 1,095,255 patients, 1,368 experienced a 30-day major adverse cardiac or cerebrovascular event, corresponding to an incidence of 0.12%.

• Major adverse cardiac and cerebrovascular events were more frequent after Roux-en-Y gastric bypass compared to sleeve gastrectomy.
• Independent predictors of perioperative events included dialysis dependence, prior heart attack, prior blood clot in the lungs, male sex, insulin-dependent diabetes, and increased antihypertensive medication use.
• Each additional antihypertensive medication was linked to higher odds of experiencing perioperative events.
• In patients with heart failure data, heart failure was also associated with increased risk of perioperative events.
• The findings indicate that perioperative cardiovascular risk is influenced more by markers of advanced systemic disease severity rather than just common comorbidities.

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