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The Protective Effects of Increasing Serum Uric Acid Level on Development of Metabolic Syndrome
Higher Blood Uric Acid Levels May Protect Against Metabolic Syndrome
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Abstract
In a study of 13,057 subjects, increasing (SUA) levels may protect against the development of (MetS).
- Higher percent changes in SUA levels are associated with lower hazard ratios for incident MetS in both males and females.
- In males, hazard ratios for developing MetS in the second, third, and fourth quartiles of SUA change were 1.055, 0.927, and 0.807, respectively.
- In females, corresponding hazard ratios were 1.000, 0.744, and 0.684.
- Each one-standard deviation increase in percent change in SUA levels was associated with a hazard ratio of 0.944 in males and 0.851 in females for incident MetS.
- These findings suggest that increasing SUA levels could have a protective effect against MetS.
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Key numbers
0.851
Decrease in Risk of (Female)
Hazard ratio for incident in females with increased levels.
0.804
Decrease in Risk of (Male)
Hazard ratio for incident in males in the fourth quartile of change.