Journal of psychopharmacology (Oxford, England)

Brainwave changes caused by psilocybin connect immediate and lasting effects

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Abstract

Psilocybin is associated with acute reductions in alpha power and increased entropy.

  • The neurophysiological effects of psilocybin may include changes in brain activity patterns.
  • Alpha power reductions suggest decreased neural synchronization during the acute phase.
  • Increased entropy may indicate a rise in the complexity of brain activity.
  • The time-course of these neurophysiological changes from administration through the 24-hour sub-acute phase is not well understood.

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