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Behavior and growth changes caused by psychedelics in zebrafish: a systematic review
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Abstract
Thirteen articles were reviewed on the effects of psychedelics in zebrafish, focusing on behavioral changes and developmental toxicity.
- Overall, psychedelics did not cause major physical abnormalities in embryo-larvae.
- High concentrations of ayahuasca led to edemas and increased mortality.
- Ibogaine, MDMA, and LSD were linked to movement issues when exposure occurred during development.
- DMT, psilocybin, and psilocin may have anxiety-reducing effects on larvae, while LSD, MDMA, mescaline, and noribogaine could lower anxiety in adult zebrafish.
- Psychedelics may be safe at low concentrations in zebrafish, but the impact on neurodevelopment in offspring remains unclear.
Simplified
Psychedelic Science