Rest-activity circadian rhythm in breast cancer survivors at 5 years after the primary diagnosis

A statistically significant circadian rhythm was found in all 28 participants, including 15 breast cancer survivors and 13 healthy controls.

• Breast cancer survivors exhibited lower activity counts compared to healthy controls, with 192.0 versus 276.4 activity counts respectively.
• The Midline Estimating Statistic of Rhythm was also reduced in breast cancer survivors compared to healthy controls, showing 167.0 versus 222.6 activity counts.
• No significant differences in the timing of rest-activity circadian rhythm were observed between the two groups, with times of 15:09 and 15:01 hr:min for breast cancer survivors and controls, respectively.
• These findings provide preliminary evidence of alterations in rest-activity circadian rhythm parameters in breast cancer survivors five years post-diagnosis.

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