Retinal patterns and the cellular repertoire of neuropsin (Opn5) retinal ganglion cells

Nov 7, 2021The Journal of comparative neurology

Patterns and types of light-sensitive retinal nerve cells called neuropsin (Opn5) ganglion cells

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Abstract

is restricted to , showing greater densities in the dorsotemporal quadrant of the retina.

  • Opn5-RGCs are nonhomogeneously distributed, indicating a specific spatial arrangement within the retina.
  • The central targets of Opn5-RGCs show a bias towards regions involved in image formation and stabilization.
  • Molecular and electrical profiling suggest that Opn5-RGCs belong to specific types that are responsive to visual stimuli like edges and motion.
  • These findings contribute to understanding the roles of atypical opsins in retinal function.

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Key numbers

520.8 ± 41.4 cells/mm
Cell Density in
Density of -expressing cells in the ()
5.9 ± 1.1 cells/mm
Cell Density in
Density of -expressing cells in the ()

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