Full text is available at the source.
REV-ERB and ROR nuclear receptors as drug targets
REV-ERB and ROR nuclear receptors as potential drug targets
AI simplified
Abstract
Recent discoveries of natural molecules that activate nuclear receptors REV-ERB and ROR suggest potential therapeutic targets for various diseases.
- REV-ERB receptors are linked to metabolism, development, immunity, and circadian rhythms.
- Recent identification of natural activators for these receptors has prompted interest in synthetic ligands.
- Targeting REV-ERB and ROR receptors may be beneficial in treating conditions such as diabetes, atherosclerosis, autoimmune diseases, and cancer.
- Pharmacological advancements indicate that these receptors could serve as effective drug targets.
AI simplified