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Abstract
RNA modifications are associated with regulating RNA metabolism and gene expression, impacting tumor evolution and immune responses.
- RNA modifications, including m6A and m1A, play critical roles in controlling transcript stability and translation efficiency.
- Dysregulation of these modifications is increasingly recognized as a hallmark of cancer.
- The interplay between RNA modifications and the tumor immune microenvironment may influence immune evasion and antigen presentation.
- Epitranscriptomic changes could affect cellular responses to chemotherapy, radiotherapy, and immunotherapy.
- This review connects descriptive mapping of RNA modifications to functional implications in tumor biology.
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