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Rotating night shift work, sleep duration and elevated gamma-glutamyl transpeptidase among steelworkers: cross-sectional analyses from a Chinese occupational cohort
Night shift work and sleep length linked to higher liver enzyme levels in steelworkers
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Abstract
Elevated (GGT) is associated with rotating night shift work among 7031 steelworkers.
- Current shift workers and those with over 19 years of night shift experience showed increased odds of elevated GGT, with odds ratios ranging from 1.34 to 1.46.
- A cumulative number of night shifts exceeding 1774 nights was linked to elevated GGT levels.
- The frequency of night shifts also influenced GGT levels, with both ≤7 nights/month and >7 nights/month associated with increased odds.
- Shorter sleep duration (<7 hours/day) did not independently contribute to elevated GGT but was significant among rotating night shift workers.
- Other lifestyle factors were found to affect the relationship between rotating night shift work and elevated GGT.
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Key numbers
1.39
Increased Odds of Elevated
Odds ratio for current night shift workers vs. never night shift workers.
1774 nights
Cumulative Night Shifts
Threshold for cumulative night shifts associated with elevated .
>19 years
Duration of Night Shifts
Threshold for duration of night shifts associated with elevated .