We can’t show the full text here under this license. Use the link below to read it at the source.
Rumen-derived lipopolysaccharide enhances the expression of lingual antimicrobial peptide in mammary glands of dairy cows fed a high-concentrate diet
Rumen bacterial toxins increase natural antimicrobial peptide in dairy cows' mammary glands on a high-concentrate diet
AI simplified
Abstract
Lactating cows on a high-concentrate diet (HCD) showed higher levels of lipopolysaccharide (LPS) in ruminal fluid and blood compared to those on a low-concentrate diet (LCD).
- Cows fed the HCD had a lower ruminal pH than those on the LCD.
- LPS concentrations were increased in the rumen, lacteal artery, and vein in the HCD group.
- Enhanced expression of antimicrobial peptides and pro-inflammatory cytokines was observed in the mammary glands of HCD-fed cows.
- LAP protein levels were significantly higher in the HCD group compared to the LCD group.
- While the expression of nuclear factor kappa B (NF-кB) remained unchanged, its activation increased in HCD-fed cows.
AI simplified