We can’t show the full text here under this license.
Abstract
A 48-year-old woman with type 2 diabetes developed persistent nausea and vomiting after resuming semaglutide at 2 mg weekly, leading to acute kidney injury due to dehydration.
- Semaglutide, a medication for type 2 diabetes, is associated with slowed gastric emptying and can induce gastroparesis.
- The patient experienced gastrointestinal symptoms after not following the recommended gradual increase in semaglutide dosage.
- Imaging revealed left-sided colitis, which was treated with antibiotics, while gastroparesis was suspected due to the medication.
- Discontinuation of semaglutide and treatment with metoclopramide led to resolution of symptoms and recovery.
- Rapid dose escalation of semaglutide may contribute to gastrointestinal complications in diabetic patients.
Simplified