European journal of case reports in internal medicine

Ischemic Colitis Linked to Semaglutide Use in a Middle-Aged Woman Without Blood Vessel Risk Factors

Updated

Abstract

A 53-year-old woman developed ischemic colitis after starting semaglutide.

  • Ischemic colitis typically occurs in patients with vascular risk factors.
  • This case presents a patient without comorbidities who experienced acute abdominal pain and bloody stools.
  • Imaging, colonoscopy, and biopsy confirmed the diagnosis of ischemic colitis.
  • Infectious testing returned negative for other causes.
  • Symptoms resolved after stopping semaglutide and providing supportive care.
  • There may be an association between glucagon-like peptide-1 receptor agonists and ischemic colitis.

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Funding

Competing interests

0 of 7
authors report competing interests
7 report none
PubMed

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