Effects of semaglutide on mental health

Oct 6, 2025Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova

Semaglutide's effects on mental health

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Abstract

Semaglutide is actively used worldwide for treating type 2 diabetes and obesity.

Reports indicate both adverse and beneficial effects of semaglutide on mental health.
A review of current scientific evidence reveals no clear consensus on semaglutide's mental health impact.
This lack of definitive findings suggests the need for further research in this area.

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Semaglutide is a glucagon-like peptide-1 receptor agonist, approved and currently actively used worldwide for the treatment of type 2 diabetes mellitus and obesity. With the growing popularity of the drug, reports of both adverse and beneficial effects of the drug on mental health have become more frequent. The purpose of this study is to review the impact of semaglutide on mental health by collecting, analyzing, and synthesizing current scientific evidence. The authors conclude that currently there is no unequivocal opinion on this matter, which opens up new horizons for future research.

Effects of semaglutide on mental health

Abstract

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