Zhurnal nevrologii i psikhiatrii imeni S.S. KorsakovaOct 6, 2025

Semaglutide's effects on mental health

GLP-1 Therapies Weekly Brief ↗PubMed ↗DOI ↗

Updated Jan 1, 2026

Abstract

Semaglutide is actively used worldwide for treating type 2 diabetes and obesity.

Reports indicate both adverse and beneficial effects of semaglutide on mental health.
A review of current scientific evidence reveals no clear consensus on semaglutide's mental health impact.
This lack of definitive findings suggests the need for further research in this area.

Simplified

Semaglutide is a glucagon-like peptide-1 receptor agonist, approved and currently actively used worldwide for the treatment of type 2 diabetes mellitus and obesity. With the growing popularity of the drug, reports of both adverse and beneficial effects of the drug on mental health have become more frequent. The purpose of this study is to review the impact of semaglutide on mental health by collecting, analyzing, and synthesizing current scientific evidence. The authors conclude that currently there is no unequivocal opinion on this matter, which opens up new horizons for future research.

Semaglutide's effects on mental health

Abstract

You found one interesting study. We’ll send the next 7.

What Lands in Your Inbox Each Week:

Recent issues from the glp-1 therapies brief

Abstract

Related papers

You found one interesting study. We’ll send the next 7.

What Lands in Your Inbox Each Week:

Recent issues from the glp-1 therapies brief