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Effect of supplemental simethicone for bowel preparation on adenoma detection during colonoscopy: A meta‐analysis of randomized controlled trials
Supplemental simethicone may improve detection of growths during colonoscopy
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Abstract
Supplemental simethicone significantly increased the adenoma detection rate (ADR) during colonoscopy from 23.3% to 27.9%.
- The analysis included six trials with a total of 1855 patients.
- The relative risk of increased ADR with supplemental simethicone was 1.20.
- A statistically significant difference in ADR was observed (P = 0.02).
- Subgroup analysis indicated that simethicone may be particularly beneficial in endoscopic centers with low baseline ADR.
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