Purification of Sinus Gland Peptides Having Vitellogenesis-Inhibiting Activity from the Whiteleg Shrimp Litopenaeus Vannamei

Seven peptides from the crustacean hyperglycemic hormone family were identified in the whiteleg shrimp, with Liv-SGP-G exhibiting the strongest vitellogenesis-inhibiting activity.

• The study characterized multiple vitellogenesis-inhibiting hormones (VIH) in the whiteleg shrimp.
• Six of the seven identified peptides significantly reduced vitellogenin mRNA levels, with varying efficacy.
• Liv-SGP-G was the most abundant peptide and showed strong inhibition of vitellogenesis.
• Liv-SGP-D did not demonstrate significant inhibitory activity on vitellogenin mRNA levels.
• The complete primary structure of Liv-SGP-G consists of 72 amino acid residues with an amidated C-terminus.

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