The effect of sleep disturbance trajectories on psychotic-like experiences among adolescents: the mediating role of depressive symptoms

A total of 7,529 adolescents participated in the study evaluating sleep disturbance and psychotic-like experiences.

• Five distinct patterns of sleep disturbance were found: no/low (72.2%), remission (8.8%), relapsing/remitting (7.4%), new-onset (8.9%), and persistent (2.7%).
• Depressive symptoms were shown to partially mediate the relationship between certain sleep disturbance patterns and psychotic-like experiences.
• The mediation effects were significant for relapsing/remitting, new-onset, and persistent sleep disturbances.
• The confidence intervals for the mediation effects were reported as 0.20-0.30, 0.42-0.53, and 0.41-0.58, respectively.
• Early screening and interventions focusing on sleep disturbance and depressive symptoms may be important to help prevent the onset of psychotic-like experiences.

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