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Sleep-wake cycle and melatonin rhythms in adolescents and young adults with mood disorders: Comparison of unipolar and bipolar phenotypes
Sleep patterns and melatonin rhythms in teens and young adults with depression or bipolar disorder
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Abstract
Patients with bipolar disorders had significantly lower levels and later onset of melatonin secretion than those with unipolar depression.
- Circadian measures may serve as early indicators for different mood disorder subtypes.
- Bipolar disorder patients exhibited later melatonin secretion compared to unipolar depression patients.
- Several patients showed abnormal timing relationships between sleep, melatonin, and body temperature.
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