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Abstract
Life stress may trigger depressive episodes by disrupting social routines and biological circadian rhythms.
- The social zeitgeber theory explains how life events can lead to mood episodes.
- Disruptions in social routines are associated with changes in biological circadian rhythms.
- There is limited data supporting the application of the social zeitgeber theory to (hypo)manic episodes.
- Circadian rhythm disruptions may also be linked to internal mechanisms, such as abnormalities in the brain's pacemaker.
- The review explores potential causes of circadian rhythm disruptions and mood episodes in unipolar and bipolar disorders.
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