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Abstract
SGLT2 inhibitor prescriptions increased from 2.5% in 2015 to 13.9% in 2021.
- The overall number of individuals prescribed oral glucose-lowering drugs rose from 2015 to 2021.
- There was a 9.2 percentage point decrease in individuals receiving monotherapy or dual combination therapy.
- The proportion of individuals receiving triple or more combination therapy increased during the same period.
- Individuals with heart failure experienced a significant rise in SGLT2i prescriptions, from 2.2% in 2015 to 16.6% in 2021.
- The mean time to SGLT2i initiation after diagnosis decreased from 249 days in 2015 to 158 days in 2019.
- Despite increased adoption, the overall use of SGLT2i among individuals with cardiovascular-renal disease remained limited.
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